Showing posts with label HPV protein. Show all posts
Showing posts with label HPV protein. Show all posts

Thursday, February 25, 2010

PDB Explorer Protein: Discription, Disease, and Real World Application.


The protein that I found interesting is called the Human Papillomavirus E2 Protein Type 16. Its pdb ID is IDTO. Many people have heard of HPV and the infection that it can cause. It is one of the most common sexually transmitted infections we know about today (cdc.gov). HPV Type 16 belongs to the papillomavirus E2 protein family and is located on the E2 gene.
This E2 gene is chain A and its function deals with nucleotide and DNA binding. Its processes are DNA replication and transcription. The E1-E2 protein complex binds to the the origin of DNA replication which allows it to regulate the replication by either activating or repressing transcription depending on its position.
Works cited:
www.cdc.gov/hpv/WhatIsHPV.html
http://www.ebi.ac.uk/msd-srv/oca/oca-bin/ocaids